Morphine to relieve exertional dyspnoea in COPD: myth, dream or reality?
نویسندگان
چکیده
Affiliations: Faculté de médecine, Université Laval, Québec, Canada. Centre de recherche de l’Institut Universitaire de Cardiologie et de Pneumologie de Québec (CRIUCPQ), Québec, Canada. Sorbonne Universités, UPMC Université Paris 06, INSERM, UMRS_1158 Neurophysiologie respiratoire expérimentale et clinique, Paris, France. Assistance Publique-Hôpitaux de Paris (AP-HP), Groupe Hospitalier Pitié-Salpêtrière Charles Foix, Service des Explorations Fonctionnelles de la Respiration, de l’Exercice et de la Dyspnée (Département “R3S”, Pôle PRAGUES), Paris, France.
منابع مشابه
Lack of effect of high doses of inhaled morphine on exercise endurance in chronic obstructive pulmonary disease.
Systemic opiates may relieve dyspnoea and improve exercise tolerance in patients with chronic obstructive pulmonary disease (COPD). Small doses of inhaled opiates may have similar effects; however, recent studies have shown no benefit. We studied higher doses of inhaled morphine and measured systemic absorption to determine whether any beneficial actions are local or systemic. Twenty and 40 mg ...
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ورودعنوان ژورنال:
- The European respiratory journal
دوره 50 4 شماره
صفحات -
تاریخ انتشار 2017